Corpus luteum element secretes inadequacy , opposite or estrogen is absolutely overmuch , hyperplasia of organization of the mammary gland in cycle of menstruation of as a result and instauration process occur disorder , make mammary gland conduit or gland bubble epithelial and proliferous , breast is in charge of dilate to become bursa state , form bump 黄体素分泌不足,雌激素相对或绝对过多,以致月经周期中乳腺组织增生和复旧过程发生紊乱,使乳腺导管或腺泡上皮增生,乳管扩张成囊状,形成肿块。